Parasite-Host Dynamics throughout Antimalarial Drug Development Stages Complicate the Translation of Parasite Clearance

Expanding the antimalarial toolkit: Targeting host–parasite interactions

Recent successes in malaria control are threatened by drug-resistant Plasmodium parasites and insecticide-resistant Anopheles mosquitoes, and first generation vaccines offer only partial protection. New research approaches have highlighted host as well as parasite molecules or pathways that could be targeted for interventions. In this study, we discuss host-parasite interactions at the differen...

Modelling within Host Parasite Dynamics of Schistosomiasis

Schistosomiasis infection is characterized by the presence of adult worms in the portal and mesenteric veins of humans as part of a complex migratory cycle initiated by cutaneous penetration of the cercariae shed by infected freshwater snails. The drug praziquantel is not always effective in the treatment against schistosomiasis at larvae stage. However, our simulations show that it is effectiv...

Actinomyces bovis a possible cause for calcification of the parasite in the host tissue

The impact of host starvation on parasite development and population dynamics in an intestinal trypanosome parasite of bumble bees.

Host nutrition plays an important role in determining the development and success of parasitic infections. While studies of vertebrate hosts are accumulating, little is known about how host nutrition affects parasites of invertebrate hosts. Crithidia bombi is a gut trypanosome parasite of the bumble bee, Bombus terrestris and here we use it as a model system to determine the impact of host nutr...

Development stages of the"rope"human intestinal parasite

This paper describes the five development stages of the rope human parasite. Rope parasites have been discovered as a result of cleansing enemas. Parasite adult stages live in human gastrointestinal tract and are anaerobic. They move inside the body by releasing gas bubbles utilizing jet propulsion. Rope parasites look like a rope, and can be over a meter long. It takes tens of years for them t...